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Table 2 Multivariable-adjusted hazard ratios for liver-related and all-cause mortality associated with alcohol intake by alanine aminotransferase (ALT) level status

From: Modest alcohol intake and mortality in individuals with elevated alanine aminotransferase levels: a nationwide cohort study

Alcohol intake Alanine aminotransferasea p for interaction
Normal
HR (95% CI)
Elevated
HR (95% CI)
Liver-related mortality    < 0.01
 None Reference Reference  
 Light 0.73 (0.51, 1.05) 1.57 (1.08, 2.28)  
 Moderate 1.06 (0.73, 1.52) 2.09 (1.46, 2.99)  
All-cause mortality    
 None Reference Reference < 0.01
 Light 0.72 (0.66, 0.77) 0.93 (0.81, 1.08)  
 Moderate 0.89 (0.82, 0.97) 1.31 (1.14, 1.50)  
  1. HRs and 95% CIs were obtained from proportional hazards models with age as time scale and adjusted for sex, body mass index, Charlson comorbidity index, diabetes, hypertension, hyperlipidemia, smoking status (never, ever or unknown), residential area (metropolitan, rural, and unknown), and income percentile (≤30th, >30th–≤70th, >70th, and unknown)
  2. Abbreviation: HR, hazard ratio; CI, confidence interval
  3. aNormal: < 34 U/L for men and < 25 U/L for women; elevated: ≥34 U/L for men and ≥25 U/L for women