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Table 3 Multivariable-adjusted hazard ratios for liver-related and all-cause mortality associated with elevated alanine aminotransferase (ALT) levels by alcohol intake status

From: Modest alcohol intake and mortality in individuals with elevated alanine aminotransferase levels: a nationwide cohort study

Alcohol intake Alanine aminotransferasea p for interaction
Normal
HR (95% CI)
Elevated
HR (95% CI)
Liver-related mortality <  0.01
 None Reference 2.84 (2.12, 3.80)  
 Light Reference 6.10 (4.03, 9.24)  
 Moderate Reference 5.63 (3.79, 8.34)  
All-cause mortality <  0.01
 None Reference 0.97 (0.90, 1.04)  
 Light Reference 1.26 (1.10, 1.45)  
 Moderate Reference 1.41 (1.24, 1.61)  
  1. HRs and 95% CIs were obtained from proportional hazards models with age as time scale and adjusted for sex, body mass index, Charlson comorbidity index, diabetes, hypertension, hyperlipidemia, smoking status (never, ever or unknown), residential area (metropolitan, rural and unknown) and income percentile (≤30th, >30th–≤70th, >70th, and unknown)
  2. Abbreviation: HR, hazard ratio; CI, confidence interval
  3. aNormal: < 34 U/L for men and <25 U/L for women; elevated: ≥34 U/L for men and ≥25 U/L for women