Fig. 2

Mean difference in offspring FMI (SD) per 1SD increase in maternal BMI, from MR (lassosum) and confounder adjusted multivariable regression (MV) models. Confounder adjusted multivariable regression (MV) estimates are from model three (see the “Methods” section). N, number of participants. The number of SNPs used for the MR analyses is provided separately by cohort in Table 1. P, P-value for the null hypothesis that the effect equals zero; P_dif, P-value for the null hypothesis that MR effect equals the MV effect