|
Genetics
|
All (n=946)
|
HFpEF# (n=415)
|
Non-HF# (n=531)
|
P value*
|
|---|
|
Mutation-positive
|
313 (33.1)
|
152 (36.6)
|
161 (30.3)
|
0.041
|
|
Multiple variants
|
6 (0.6)
|
4 (1.0)
|
2 (0.4)
|
0.413
|
|
MYH7
|
151 (16.0)
|
74 (17.8)
|
77 (14.5)
|
0.165
|
|
MYBPC3
|
127 (13.4)
|
56 (13.5)
|
71 (13.4)
|
0.956
|
|
ACTC1
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
|
-
|
|
MYL2
|
6 (0.6)
|
4 (1.0)
|
2 (0.4)
|
0.413
|
|
MYL3
|
4 (0.4)
|
3 (0.7)
|
1 (0.2)
|
0.325
|
|
TNNI3
|
16 (1.7)
|
8 (1.9)
|
8 (1.5)
|
0.618
|
|
TNNT2
|
13 (1.4)
|
9 (2.2)
|
4 (0.8)
|
0.064
|
|
TPM1
|
2 (0.2)
|
1 (0.2)
|
1 (0.2)
|
1.000
|
- AHA American Heart Association, HCM hypertrophic cardiomyopathy, HFpEF heart failure with preserved ejection fraction, non-HF patients without heart failure
- #Heart failure phenotypes were identified using AHA criteria
- *Comparison between patients with HFpEF and non-HF patients
