Table 3 Certainty of the evidence for outcomes of the main analysis
Outcome | № of included studies | Certainty of the evidence (GRADE) | Relative effect (95% CI) |
|---|---|---|---|
Overall complications | 11 (retrospective) | ⨁⨁◯◯ LOW | OR 1.55 [1.05; 2.29] |
Major complications | 8 (retrospective) | ⨁⨁◯◯ LOW | OR 1.97 [1.13; 3.43] |
Minor complications | 8 (retrospective) | ⨁◯◯◯ VERY LOW | OR 0.72 [0.41; 1.29] |
PHLF | 6 (retrospective) | ⨁◯◯◯ VERY LOW | OR 1.83 [0.86; 3.91] |
Postoperative biliary leakage | 8 (retrospective) | ⨁⨁◯◯ LOW | OR 1.43 [0.77; 2.63] |
Postoperative hemorrhage | 5 (retrospective) | ⨁⨁◯◯ LOW | OR 1.76 [1.23; 2.50] |
Postoperative infection | 8 (retrospective) | ⨁⨁◯◯ LOW | OR 1.63 [1.03; 2.57] |
Perioperative mortality | 2 (retrospective) | ⨁◯◯◯ VERY LOW | OR 4.84 [0.00; 41157788.03] |
90-days mortality | 5 (retrospective) | ⨁⨁◯◯ LOW | OR 1.55 [0.76; 3.15] |
1-year overall survival | 5 (retrospective) | ⨁⨁◯◯ LOW | OR 0.83 [0.32; 2.14] |
5-years overall survival | 6 (retrospective) | ⨁⨁◯◯ LOW | OR 1.07 [0.79; 1.45] |
Recurrence | 4 (retrospective) | ⨁⨁◯◯ LOW | OR 1.06 [0.87; 1.30] |
1-year recurrence-free survival | 4 (retrospective) | ⨁⨁◯◯ LOW | OR 0.95 [0.47; 1.92] |
5-year recurrence-free survival | 5 (retrospective) | ⨁⨁◯◯ LOW | OR 1.20 [0.91; 1.59] |