Fig. 2

Change of Montreal Cognitive Assessment (MoCA) score over time. Patients were grouped by whether they were prescribed neural network treatment of choice (NNToC) according to the Long Short Term Memory (LSTM) model. The X-axis represents the duration of taking a particular medication, where x = 0 means the treatment initiation time. Data shown are mean values, with error bars indicating standard deviation. External validation on Oxford Health NHS Foundation Trust (OHFT). One hundred sixty [14.20%] patients were prescribed NNToC and reported a smaller MoCA reduction after 1.75 years compared to the 967 [85.80%] patients who were not (1.03 [0.19] vs 1.56 [0.21], respectively; P = 0.09). A detailed quantitative report of score changes is provided in Additional file 1: Table S5