Skip to main content

Table 1 Tumor characteristics in different ethnic groups: data from the Prospective study of Outcomes in Sporadic versus Hereditary breast cancer [50]

From: The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology

Tumor characteristic

Alla, n = 2956

White, n = 2690

Black, n = 118

Asian, n = 87

 

Tumor diameter median

22.0

22.0

26.00

26.00

W vs. B p=0.01

Multifocal distribution

29.9%

24.64%

38.55%

32.69%

W vs. B p = 0.004

Nodal stage

 N0

48.9%

49.2%

43.9%

48.2%

p = NS

 N1

51.2%

50.8%

56.1%

51.8%

Distant metastases

2.5%

2.4%

5.1%

3.5%

p = NS

Grade

 1

5.7%

5.6%

0.9%

11.8%

W vs. B p = 0.055

W vs. A p = 0.045

B vs. A p = 0.004

 2

33.8%

34.0%

30.0%

28.2%

 3

60.6%

60.4%

68.1%

60.0%

 Missing

2.7%

2.5%

4.2%

2.3%

ER positiveb

66.1%

66.5%

62.4%

57.5%

NS

ER negative

33.9%

33.5%

37.6%

42.5%

Missing

0.4%

0.4%

0.9%

0.0%

HER2 positiveb

28.1%

28.3%

20.2%

29.7%

NS

HER2 negative

72.0%

71.7%

79.8%

70.3%

Missing

13.5%

13.7%

7.6%

14.9%

TNTc

19.0%

18.6%

26.1%

23.2%

W vs. B = 0.043

Missing

4.2%

4.2%

2.5%

5.8%

  1. Abbreviations: ER estrogen receptor, HER2 human epidermal growth factor receptor 2PR ¼ progesterone receptor, TNT triple-negative
  2. aIncludes patients in an other or missing/unknown ethnic group
  3. bIncludes data from TMA as well as primary POSH data
  4. cIncludes patients with an ER-negative, HER2-negative, and PR-negative status. p-values obtained from the Pearson’s chi-squared test between ethnic groups and each categorical variable (excluding other ethnic groups and missing/unknown data)