Skip to main content

Table 2 Outcome events according to estimated glomerular filtration rate

From: The impact of kidney function in patients on antithrombotic therapy: a post hoc subgroup analysis focusing on recurrent bleeding events from the AFIRE trial

 

Estimated glomerular filtration rate (mL/min)

Total, N = 2092

P value

≥ 50, N = 1386

< 50, N = 706

Patients no. of bleeding

 0

1154 (83.3%)

575 (81.4%)

1729 (82.6%)

.546

 1

171 (12.3%)

90 (12.7%)

261 (12.5%)

 2

42 (3.0%)

26 (3.7%)

68 (3.3%)

 3

14 (1.0%)

9 (1.3%)

23 (1.1%)

 4

2 (0.1%)

3 (0.4%)

5 (0.2%)

 5

1 (0.1%)

1 (0.1%)

2 (0.1%)

 6

0 (0.0%)

1 (0.1%)

1 (0.0%)

 7

1 (0.1%)

0 (0.0%)

1 (0.0%)

 9

1 (0.1%)

0 (0.0%)

1 (0.0%)

 10

0 (0.0%)

1 (0.1%)

1 (0.0%)

Severe bleeding

 0

1336 (96.4%)

669 (94.8%)

2005 (95.8%)

.096

 1

45 (3.2%)

30 (4.2%)

75 (3.6%)

 2

4 (0.3%)

7 (1.0%)

11 (0.5%)

 3

1 (0.1%)

0 (0.0%)

1 (0.0%)

Hemorrhagic stroke

11 (0.8%)

6 (0.8%)

17 (0.8%)

.892

Any bleeding

232 (16.7%)

131 (18.6%)

363 (17.4%)

.300

Ischemic stroke

26 (1.9%)

21 (3.0%)

47 (2.2%)

.109

Myocardial infarction

11 (0.8%)

9 (1.3%)

20 (1.0%)

.285

Unstable angina requiring revascularization

17 (1.2%)

12 (1.7%)

29 (1.4%)

.381

Systemic embolization

0 (0.0%)

3 (0.4%)

3 (0.1%)

.015

All-cause death

42 (3.0%)

69 (9.8%)

111 (5.3%)

< .001