| Effect due to estimated glomerular filtration rate, 50 mL/min | 95% CI | P value |
---|---|---|---|
Hazard ratio for the first bleeding | |||
 Unadjusted | 0.830 | 0.670–1.028 | .088 |
 Adjusted | 0.875 | 0.701–1.090 | .234 |
Hazard ratio for the first event among the composite of bleeding, ischemic cardiovascular event, and any cause of death | |||
 Unadjusted | 0.677 | 0.567–0.809 | .000 |
 Adjusted | 0.723 | 0.603–0.867 | .000 |
Rate ratios for recurrent bleeding | |||
 Poisson (unadjusted) | 0.738 | 0.615–0.886 | .001 |
 Negative binomial (adjusted) | 0.860 | 0.680–1.088 | .208 |
Rate ratios for composite of recurrent bleeding, the first ischemic cardiovascular event, and any cause of death | |||
 Poisson (unadjusted) | 0.616 | 0.531–0.716 | .000 |
 Negative binomial (adjusted) | 0.742 | 0.615–0.896 | .002 |