Skip to main content

Table 1 Characteristics of patients receiving symptomatic FIT tests by study inclusion status and outcome

From: Combining faecal immunochemical testing with blood test results for colorectal cancer risk stratification: a consecutive cohort of 16,604 patients presenting to primary care

  All FIT tests Included Cancer
  n % n % n %
Total 18,656 100 16,604 100 139 100
Age
 0-18 95 1 0 0 0 0
 18-39.9 1,651 9 1,390 8 9 6
 40-49.9 2,553 14 2,278 14 12 9
 50-59.9 4,679 25 4,181 25 20 14
 60-69.9 3,186 17 2,892 17 21 15
 70-79.9 3,711 20 3,330 20 36 26
 ≥ 80 2,781 15 2,533 15 41 29
 Median (IQR) 61 (50, 74) 61 (51, 75) 72 (57, 81)
Sex
 Male 7,926 42 7,019 42 83 60
 Female 10,728 58 9,585 58 56 40
 Unknown 2 0 0 0 0 0
FIT (µg Hb/g)       
 0-1.9 15,298 82 13,757 83 5 4
 2-9.9 1,409 8 1,318 8 6 4
 10-99.9 1,072 6 1,023 6 51 37
 ≥ 100 539 3 506 3 77 55
 Missing 338 2 0 0   
 Median (IQR) 0 (0, 0.7) 0.2 (0, 0.8) 135.5 (33.4, 450)
Blood test results*
 Low haemoglobina 5,186 31 5,076 31 72 52
 High plateletsb 556 3 546 3 13 9
 High white cellsc 832 5 820 5 9 6
 Low mean cell haemoglobind 2,792 17 2,730 16 47 34
 Low mean cell volumee 1,014 6 980 6 30 22
 Any abnormal FBC 6,521 35 6,392 38 81 58
 Low serum ferritinf 2,015 22 1,962 22 36 40
 High serum ferriting 457 5 444 5 3 3
 High C-reactive proteinh 1,748 14 1,720 14 31 31
Clinical indication - GP reported
 Abdominal pain 3,299 18 2,941 18 23 17
 Blood in stool 1,759 9 1,451 9 22 16
 Melaena 298 2 238 1 0 0
 Change in bowel habit  7,511 40 6,656 40 45 32
 Diarrhoea 2,651 14 2,315 14 13 9
 Constipation 722 4 608 4 1 1
 Fatigue 199 1 193 1 1 1
 Rectal pain 106 1 95 1 0 0
 Bloating 594 3 541 3 2 1
 Family history of cancer 342 2 263 2 2 1
 Weight loss 1,448 8 1,348 8 9 6
Blood - GP reported
 Anaemia (any) 4,517 24 4,272 26 48 35
 Iron deficiency anaemia 1,926 10 1,793 11 18 13
 Thrombocytosis 216 1 204 1 2 1
  1. Any abnormal full blood count (FBC) refers to any abnormal result of heamoglobin, platelets, white cells, mean cell haemoglobin and mean cell volume
  2. Note: Serum ferritin and c-reactive protein tests were only conducted for a subset of patients (n = 8,922 and 12,201 respectively)
  3. IQR Interquartile range
  4. *percent with non-missing values
  5. a <130 g/L in men and <120 g/L in women
  6. b >400 μL/L
  7. c >11,000/mL
  8. d <27.4 pg/cell
  9. e <80 fL
  10. f <20 ng/mL
  11. g ≥350 ng/mL
  12. h >10 mg/L