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Table 4 Adverse obstetric and neonatal outcomes in cone-length groups, compared to the normal cytology group, adjusted multivariable logistic regression analyses

From: Associations between cervical intraepithelial neoplasia during pregnancy, previous excisional treatment, cone-length and preterm delivery: a register-based study from western Sweden

 

Normal cytology group

N=42,398

Treated, cone-length ≤10 mm

N=1805

Treated, cone-length 11–12 mm

N=361

Treated, cone-length 13–15mm

N=174

Treated, cone-length >15mm

N=68

N (%)

N (%)

aORa

p

N (%)

aORa

p

N (%)

aORa

p

N (%)

aORa

p

PTD, <37 weeks

1794 (4.2)

119 (6.6)

1.53 (1.26–1.86)

<0.001

33 (9.1)

2.19 (1.52–3.15)

<0.001

20 (11.5)

2.79 (1.74–4.48)

<0.001

15 (22.1)

5.90 (3.28–10.59)

<0.001

Spontaneous PTD

1264 (3.0)

93 (5.2)

1.72 (1.38–2.15)

<0.001

27 (7.5)

2.58 (1.73–3.85)

<0.001

17 (9.8)

3.40 (2.05–5.65)

<0.001

12 (17.6)

6.63 (3.51–12.52)

<0.001

pPROM

479 (1.1)

53 (2.9)

2.33 (1.73–3.12)

<0.001

15 (4.2)

3.42 (2.01–5.82)

<0.001

6 (3.4)

2.80 (1.23–6.39)

0.014

9 (13.2)

11.68 (5.64–24.18)

<0.001

PROM, delivery at ≥ 37 weeks

2084 (5.1)

113 (6.7)

1.17 (0.96–1.43)

0.12

30 (9.1)

1.67 (1.14–2.45)

0.009

9 (5.8)

1.09 (0.55–2.15)

0.81

10 (18.9)

4.12 (2.04–8.29)

<0.001

Chorioamnionitis

97 (0.2)

7 (0.4)

1.29 (0.59–2.82)

0.52

1 (0.3)

1.01 (0.14–7.33)

0.99

0

1 (1.5)

6.06 (0.81–45.38)

0.080

Neonatal sepsis

591 (1.4)

31 (1.7)

1.02 (0.71–1.47)

0.92

5 (1.4)

0.87 (0.36–2.13)

0.77

3 (1.7)

1.12 (0.36–3.53)

0.85

6 (8.8)

5.72 (2.43–13.47)

<0.001

  1. Statistically significant p values in bold type
  2. aAnalyses adjusted for year of delivery, maternal age, parity, BMI, marital status, country of birth, infant’s sex, smoking, income, education level, and assisted reproduction
  3. aOR, adjusted odds ratio; CI, confidence interval; mm, millimeter; N, number; OR, odds ratio; pPROM, preterm prelabor rupture of membranes; PROM, prelabor rupture of membranes; PTD, preterm delivery