Associations between cervical intraepithelial neoplasia during pregnancy, previous excisional treatment, cone-length and preterm delivery: a register-based study from western Sweden

Table 5 Adverse obstetric and neonatal outcomes in cone-length groups up to 10 mm, compared to the normal cytology group, adjusted multivariable logistic regression analyses

	Normal cytology group N=42,398	Treated, cone-length <6 mm N=212			Treated, cone-length 6–9 mm N=1219			Treated, cone-length 10 mm N=374
	N (%)	N (%)	aOR^a	p	N (%)	aOR^a	p	N (%)	aOR^a	p
PTD, <37 weeks	1794 (4.2)	16 (7.5)	1.72 (1.03–2.89)	0.038	77 (6.3)	1.47 (1.16–1.87)	0.002	26 (7.0)	1.57 (1.05–2.36)	0.028
Spontaneous PTD	1264 (3.0)	12 (5.7)	1.83 (1.02–3.31)	0.044	61 (5.0)	1.68 (1.29–2.20)	<0.001	20 (5.3)	1.75 (1.11–2.76)	0.017
pPROM	479 (1.1)	7 (3.3)	2.55 (1.19–5.49)	0.016	36 (3.0)	2.36 (1.66–3.34)	<0.001	10 (2.7)	2.07 (1.09–3.92)	0.026
PROM, delivery at ≥ 37 weeks	2084 (5.1)	11 (5.6)	0.93 (0.50–1.71)	0.81	79 (6.9)	1.23 (0.97–1.55)	0.09	23 (6.6)	1.14 (0.74–1.75)	0.55
Chorioamnionitis	97 (0.2)	0	–	–	4 (0.3)	1.11 (0.40–3.05)	0.84	3 (0.8)	2.73 (0.85–8.76)	0.09
Neonatal sepsis	591 (1.4)	3 (1.4)	0.79 (0.25–2.48)	0.69	22 (1.8)	1.09 (0.71–1.68)	0.70	6 (1.6)	0.95 (0.42–2.14)	0.90

Statistically significant p values in bold type
^aAnalyses adjusted for: year of delivery, maternal age, parity, BMI, marital status, country of birth, infant’s sex, smoking, income, education level, and assisted reproduction
aOR, adjusted odds ratio; CI, confidence interval; mm, millimeter; N, number; OR, odds ratio; pPROM, preterm prelabor rupture of membranes; PROM, prelabor rupture of membranes; PTD, preterm delivery.

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