From: The relationships between women’s reproductive factors: a Mendelian randomisation analysis
Exposure | N | F statistic | R2 | nSNPs |
---|---|---|---|---|
Age at menarche | 243,898 | 74.95 (75.28 for outcome AFS) | 0.064 | 223 (222 for outcome AFSa) |
Age at menopause | 143,791 | 85.08 | 0.047 | 84 |
Age at first live birth | 203,606 | 41.97 | 8.38 × 10−3 | 41 |
Age at last live birth | 203,356 | 43.46 | 1.92 × 10−3 | 9 |
Number of live births | 250,746 | 46.75 | 1.68 × 10−3 | 9 |
Age first had sexual intercourse | 219,486 | 39.46 | 9.44 × 10−3 | 53 |
Lifetime number of sexual partners | 208,274 | 39.20 | 6.36 × 10−3 | 34 |
Ever parous status | 250,746 | 53.92 | 8.59 × 10−4 | 4 |