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Fig. 1 | BMC Medicine

Fig. 1

From: Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes

Fig. 1

Clinical features and fat distribution in patients. A Results of dual-energy X-ray absorptiometry (DXA)-scan showing body composition in patient 1 with total and segmental fat distribution. B Left panel: Results of DXA-scan showing body composition in patient 2 with total and segmental fat distribution. Right panel: Front picture of patient 2 (trunk and legs) showing lipoatrophy of the whole body and muscular hypertrophy (upper and lower limbs). C Whole body magnetic resonance imaging (MRI) in patient 3 (left panel), as compared to a female control (right panel) showing subcutaneous fat loss in a generalized pattern in patient 3. Whole body pictures (I) correspond to coronal T1-weighted images. Other images are T1-weighted slices. IIa: retroorbital, IIb: supraclavicular, IIIa: trunk, IIIb: upper abdomen showing severe hepatic steatosis in patient 3, IIIc: lower abdomen/pelvic, and IV: proximal lower limbs

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BMC Medicine

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