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Fig. 5 | BMC Medicine

Fig. 5

From: Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

Fig. 5

Association between elevated sphingolipids and aggressive-variant prostate cancer (AVPC), and their combined impact on clinical outcomes. A Heatmap of sphingolipids with significantly elevated levels in men with the AVPC signature, compared to men without. Sphingolipids which are also elevated in the validation cohort are asterisked. Cer(d18:1/24:1), which is a component of the 3-lipid signature, is bolded. Kaplan-Meier analysis of overall survival by molecular AVPC signature and 3-lipid signature in B the discovery cohort and C the validation cohort

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BMC Medicine

ISSN: 1741-7015

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