Structured reporting to improve transparency of analyses in prognostic marker studies

Table 2 Generic REMARK profile

Part a: Patients, treatments, and variables
Study and marker	Remarks
Marker	M = main predictor
Further variables	v1, v2, v3, etc.
Patients	n	Remarks
Assessed for eligibility		Disease
		Patient source
Excluded		Numbers and reasons for exclusions
Included		Inclusion criteria
Outcome(s) and number of events		Overall, perhaps also in subgroups
Part b: Statistical analyses
Analysis	Patients	Events	Variables considered	Results/remarks
IDA: initial data analysis	n	m	V1, V2, ...	For example, description of patient characteristics, data screening, handling of missing data
A1: univariable analysis of M			M	Page in manuscript, table, or figure
A2: model 1 or subgroup or sensitivity analysis
C1: model evaluation or diagnostics, check of assumptions
A3: model 2
P1: presentation of function

ISSN: 1741-7015