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Fig. 4 | BMC Medicine

Fig. 4

From: Organ-specific metastatic landscape dissects PD-(L)1 blockade efficacy in advanced non-small cell lung cancer: applicability from clinical trials to real-world practice

Fig. 4

A metastasis-based scoring system (METscore) incorporating prognostic and predictive effects for ICI prediction in the PD-L1-positive population. A Nomogram illustrating scaled points as proxy for prognostic and predictive effects of metastatic organs, and the total points as METscore for the prediction of overall survival of PD-L1-positvive patients following ICI therapy. B Putative cut-points (0 ~ 5) of METscore to stratify PD-L1-positive patients into -High and -Low groups with significantly different OS in the atezolizumab-treated population from OAK. Abbreviations: Met, metastasis; Non, non-metastasis; CI, confidence interval; OS, overall survival; ICI, immune checkpoint inhibitor; PD-L1, programmed cell death-ligand 1

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