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Fig. 3 | BMC Medicine

Fig. 3

From: Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification

Fig. 3

Proportion of breast cancer patients identified as being at high-risk within 5-year age groups. Proportions are presented by case-type (incident [i.e. enrolled within one year of diagnosis date] and prevalent). Criteria: (1) at least one first degree relative diagnosed with breast or ovarian cancer [FH], (2) 5-year absolute risk above 1.3% estimated by PRS [PRS], (3) 5-year absolute risk above 1.3% estimated by Gail risk model [Gail], and (4) carriership of PTV in ATM, BRCA1, BRCA2, CHEK2, PALB2, BARD1, RAD51C, RAD51D, or TP53 [PTV]

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BMC Medicine

ISSN: 1741-7015

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