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Table 1 Description of 7600 breast cancer patients diagnosed between ages 30 and 70. Patients were recruited as part of the Singapore Breast Cancer Cohort (SGBCC) and the Malaysian Breast Cancer Genetic Study (MyBrCa). The description of the study is in Additional file Table S4. IQR interquartile range

From: Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification

Variable Statistic
Median age at diagnosis (IQR) 52 (45–59)
Study
 SGBCC 4284 (56%)
 MyBrCa 3316 (44%)
Case-type
 Incidence (enrolled within one year of diagnosis) 4511 (59%)
 Prevalence 3087 (41%)
 Missing 2 (0%)
Ethnicity
 Chinese 5724 (75%)
 Malay 1145 (15%)
 Indian 645 (8%)
 Other 82 (1%)
 Unknown 4 (0%)
Age at menarche, years, n (%)
 ≥14 2212 (29%)
 12 to 13 3968 (52%)
 <12 803 (11%)
 Unknown 617 (8%)
Age at first birth, years, n (%)
 <20 335 (4%)
 20 to 25 1479 (19%)
 25 to 30 2289 (30%)
 ≥30 1792 (24%)
 Nulliparous 1294 (17%)
 Unknown 411 (5%)
Family history of breast cancer
 No 6364 (84%)
 Yes 1132 (15%)
Number of first degree relatives with ovarian cancer  
 No 7444 (98%)
 Yes 151 (2%)
Carriers of breast cancer predisposition genes, n (%)
 Non-carrier 7215 (95%)
 Carrier 385 (5%)
Median 5-year absolute risk (IQR)
 Gail model relative risk 0.9 (0.7–1.2)
 Polygenic risk score (PRS) 1.1 (0.7–1.6)