|
Median age at diagnosis (IQR)
|
52 (45–59)
|
|
Study
|
|
SGBCC
|
4284 (56%)
|
|
MyBrCa
|
3316 (44%)
|
|
Case-type
|
|
Incidence (enrolled within one year of diagnosis)
|
4511 (59%)
|
|
Prevalence
|
3087 (41%)
|
|
Missing
|
2 (0%)
|
|
Ethnicity
|
|
Chinese
|
5724 (75%)
|
|
Malay
|
1145 (15%)
|
|
Indian
|
645 (8%)
|
|
Other
|
82 (1%)
|
|
Unknown
|
4 (0%)
|
|
Age at menarche, years, n (%)
|
|
≥14
|
2212 (29%)
|
|
12 to 13
|
3968 (52%)
|
|
<12
|
803 (11%)
|
|
Unknown
|
617 (8%)
|
|
Age at first birth, years, n (%)
|
|
<20
|
335 (4%)
|
|
20 to 25
|
1479 (19%)
|
|
25 to 30
|
2289 (30%)
|
|
≥30
|
1792 (24%)
|
|
Nulliparous
|
1294 (17%)
|
|
Unknown
|
411 (5%)
|
|
Family history of breast cancer
|
|
No
|
6364 (84%)
|
|
Yes
|
1132 (15%)
|
|
Number of first degree relatives with ovarian cancer
| |
|
No
|
7444 (98%)
|
|
Yes
|
151 (2%)
|
|
Carriers of breast cancer predisposition genes, n (%)
|
|
Non-carrier
|
7215 (95%)
|
|
Carrier
|
385 (5%)
|
|
Median 5-year absolute risk (IQR)
|
|
Gail model relative risk
|
0.9 (0.7–1.2)
|
|
Polygenic risk score (PRS)
|
1.1 (0.7–1.6)
|
