Table 2 Differences between spontaneous and elective preterm birth in the human placental proteome

26

AAT

P01009

α-1-antitrypsin (isoform 1 or 2)

5.37/ 46.7¹ (5.37/ 44.3¹)

4.93 60

(− 1.09)

− 1.53

32

AHSG

P02765

α-2-HS-glycoprotein (inactive protein with propeptide)

5.43/ 39.3 (4.53/ 30.2)

4.56 57

(− 1.15)

− 1.77

18

ALB

P02768

Serum albumin (isoform 1)

5.92 69 (5.67/ 66.5)

5.71 66

(1.21)

− 1.52

19

ALB

P02768

Serum albumin (isoform 1)

5.76 66

(1.15)

− 1.51

20

ALB

P02768

Serum albumin (isoform 1)

5.82 66

(1.14)

− 1.57

64

ANXA4

P09525

Annexin A4 (isoform 1)

5.83/ 35.9 (5.84/ 35.8)

5.66 30

− 2.03

− 1.97

83

ANXA5

P08758

Annexin A5

4.93/ 35.9 (4.93/ 35.8)

4.90 18

(1.58)

2.08

40

BASP1

P80723

Brain acid soluble protein 1 (isoform 1)

4.62/ 22.7 (4.62/ 22.6)

4.54 50

− 2.42

− 3.23

81

CFL1

P23528

Cofilin-1

8.22/ 18.5 (8.26/ 18.4)

6.01 19

(− 1.15)

− 2.43

71

CLIC3

O95833

Chloride intracellular channel protein 3

5.99/ 26.6

5.89 26

− 1.75

(− 1.69)

66

CLIC4

Q9Y696

Chloride intracellular channel protein 4

5.45/ 28.8 (5.45/ 28.6)

5.39 26

(1.05)

− 1.56

76

CSH1/2

P0DML2/3

Chorionic somatomammotropin hormone 1/2 (isoform 1)

5.35/ 25.0¹ (5.33/ 22.3¹)

5.43 22

3.22

3.14

77

CSH1/2

P0DML2/3

Chorionic somatomammotropin hormone 1/2 (isoform 1)

5.59 22

(2.17)

2.08

86*

CSH1/2

P0DML2/3

Chorionic somatomammotropin hormone 1/2 (isoform 1, fragment)

5.67 15

(2.07)

3.09

65

EFHD1

Q9BUP0

EF-hand domain-containing protein D1 (isoform 1)

5.34/ 26.9

5.22 28

− 2.01

− 2.48

22

ERO1L

Q96HE7

ERO1-like protein α

5.48/ 54.4 (5.37/ 51.9)

5.53 63

− 1.66

− 2.78

16

EZR

P15311

Ezrin

5.94/ 69.4 (5.95/ 69.3)

5.88 82

− 2.01

− 2.69

15

F13A1

P00488

Coagulation factor XIII A chain (inactive protein with propeptide)

5.75/ 83.3 (5.81/ 79.2)

5.74 88

2.09

1.98

70

GSTO1

P78417

Glutathione S-transferase ω-1 (isoform 1)

6.24/ 27.6 (6.23/ 27.4)

5.69 27

(− 1.65)

− 2.02

42

HP

P00738

Haptoglobin (isoform 1 or 2)

4.79 44

2.19

(1.47)

52

HSD17B1

P14061

Estradiol 17-β-dehydrogenase 1

5.46/ 34.9 (5.47/ 34.8)

5.46 35

(1.35)

1.64

53

HSD17B1

P14061

Estradiol 17-β-dehydrogenase 1

5.59 35

(1.43)

1.70

17

HSPA5

P11021

78 kDa glucose-regulated protein

5.07/ 72.3 (5.01/ 70.5)

5.01 71

(1.99)

2.78

21

HSP90B1

P14625

Endoplasmin

4.76/ 92.5 (4.73/ 90.2)

5.09 97

(1.88)

1.85

43

KRT19

P08727

Keratin, type I cytoskeletal 19

5.05/ 44.2

4.85 41

(− 1.11)

− 1.74

44

KRT19

P08727

Keratin, type I cytoskeletal 19

4.87 41

(− 1.18)

− 1.76

45

KRT19

P08727

Keratin, type I cytoskeletal 19

4.90 41

(− 1.22)

(− 1.59)

46

KRT19

P08727

Keratin, type I cytoskeletal 19

4.93 41

(− 1.22)

− 1.64

56*

KRT19

P08727

Keratin, type I cytoskeletal 19 (C-terminal fragment)

4.74 37

(− 1.04)

− 1.70

34

LUM

P51884

Lumican

6.16/ 38.4 (6.17/ 36.7)

4.51 53

(1.44)

− 1.81

68

PRDX4

Q13162

Peroxiredoxin-4

5.86/ 30.5 (5.54/ 26.6)

5.61 25

(− 1.22)

− 1.55

75

PRDX6

P30041

Peroxiredoxin-6

6.00/ 25.0 (6.02/ 24.9)

5.82 25

− 1.66

− 1.69

47

SERPINB2

P05120

Plasminogen activator inhibitor 2

5.46/ 46.6

5.51 42

(1.55)

1.96

88

S100A6

P06703

Protein S100-A6

5.32/ 10.2

4.95 10

(− 1.17)

− 2.19

41

VIM

P08670

Vimentin

5.05/ 53.7 (5.05/ 53.5)

4.71 44

(1.05)

− 1.54

29

WARS

P23381

Tryptophan-tRNA ligase (isoform 1 or 2)

5.83/ 53.2¹ (5.83/ 53.0¹)

5.83 55

(− 1.02)

1.65

24

–

–

–

–

5.52 56

1.39

2.39

69

–

–

–

–

5.94 29

− 3.92

(− 2.51)

72

–

–

–

–

5.15 25

(− 1.79)

− 2.52

82

–

–

–

–

4.94 19

− 2.49

− 2.39