Skip to main content

Table 1 Baseline clinical characteristics of the male study population

From: Recovery of serum testosterone levels is an accurate predictor of survival from COVID-19 in male patients

  Mild-moderate
N=114
Severe-recovered
N=97
Severe-deceased
N=38
p-value1–2 p-value1-3 p-value2–3
Age (years), median (IQR) 59 (56–63) 56 (53–59) 68 (67–71) 0.1096 0.0001 <0.0001
Length of stay (days), median (IQR) 8 (7–9) 30.5 (27–34) 19 (9–26) <0.0001 <0.0001 0.0009
Comorbidity, n° (%) 54 (47.36) 57 (58.76) 28 (73.68) 0.1279 0.0051 0.1175
Hypertension 35 (30.70) 31 (31.96) 21 (55.26) 0.8822 0.0109 0.0178
Diabetes 20 (17.54) 15 (16.46) 11 (28.95) 0.7143 0.1630 0.0908
Cancer 6 (5.26) 3 (3.09) 3 (7.89) 0.5115 0.6915 0.3497
Cardiovascular diseases 9 (7.89) 12 (12.37) 3 (7.89) 0.3573 0.9999 0.5560
Chronic Lung diseases 10 (8.77) 6 (6.19) 5 (13.16) 0.6046 0.5297 0.2912
Obesity-Dyslipidaemia 16 (14.03) 33 (34.02) 11 (28.95) 0.0009 0.0497 0.6842
Chronic Kidney disease 6 (5.26) 2 (2.06) 1 (2.63) 0.2927 0.6808 0.6727
Others 9 (7.89) 13 (13.4) 7 (18.42) 0.2586 0.1220 0.5903
Biochemical parameters, median (IQR)
Testosterone 144.3 (112.3–189.3) 52.91 (45.03–66.73) 58.48 (46.83–81.94) <0.0001 <0.0001 0.9999
Leucocytes n° 6.32 (5.78–6.88) 7.80 (6.83–8.80) 8.70 (7.20–9.65) <0.0001 0.0051 0.9999
Lymphocytes n° 1.20 (1.0–1.4) 0.77 (0.70–0.82) 0.8 (0.65–0.90) <0.0001 0.0001 0.9999
Lymphocytes % 18.55 (16.15–1.57) 9.20 (8.18–11.28) 10.89 (7.95–13.38) <0.0001 <0.0001 0.9999
Neutrophils 4.57 (3.92–4.90) 6.26 (5.53–7.38) 6.39 (5.53–8.34) <0.0001 0.0007 0.9999
Interleukine-6 42.30 (25.33–53.46) 130.8 (112.10–160.6) 215.30 (117.6–996.4) <0.0001 <0.0001 0.9999
C-reactive protein 9.57 (6.76–10.88) 17.47 (12.17–0.72) 14.56 (9.84–24.019) <0.0001 0.0069 0.9999
LDH 324 (296.0–369.0) 472.5 (440.0–506.0) 493.0 (429.0–583.0) <0.0001 <0.0001 0.9999
D-Dimer 236 (213.0–311.0) 529.0 (361.0–711.0) 421.5 (260.0–684.0) <0.0001 0.0210 0.9999
Ferritin 934 (679.0–1089.0) 1289 (1100.0–1574.0) 1443.0 (554.9–1919.0) 0.0022 0.7403 0.6783
  1. The Fisher’s exact test was used to compare comorbidities. The Kruskal-Wallis test with Dunn’s multiple comparison was used to analyze the length of stay and biochemical parameters
  2. 1Mild-moderate group, 2Severe-recovered group, 3Severe-deceased group