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Table 1 Baseline characteristics of 65,684 participants in the risk prediction population by incident type 2 diabetes status

From: Predictive value of circulating NMR metabolic biomarkers for type 2 diabetes risk in the UK Biobank study

Baseline characteristicsa

Incident type 2 diabetes

Total

Yes

No

No. of participants

1719

63,965

65,684

Age, sex and socioeconomic factors

 Mean age (SD), years

57.1 (7.7)

55.1 (8.0)

55.2 (8.0)

 Women, %

47

58

58

 Townsend Deprivation Index (SD)b

0.3 (1.1)

0.0 (1.0)

0.0 (1.0)

Lifestyle factors

 Smoking, %

   

  Never or occasional

54

61

61

  Previous

33

32

32

  Current regular

14

7

7

 Alcohol drinking, %

   

  Never or occasional

42

25

26

  Previous

5

3

3

  Current regular

53

71

71

Physical and blood-based measurements, mean (SD)

 BMI, kg/m2

31.5 (5.2)

26.8 (4.5)

26.9 (4.4)

 WC, cm

100 (13)

88 (12)

88 (13)

 HC, cm

110 (10)

103 (9)

103 (9)

 WHR

0.91 (0.08)

0.86 (0.09)

0.86 (0.09)

 SBP, mmHg

142 (19)

136 (18)

136 (18)

 DBP, mmHg

86 (11)

82 (10)

82 (10)

 Total cholesterol, mmol/Lc

6.0 (1.1)

5.9 (1.1)

5.9 (1.1)

 LDL cholesterol, mmol/Lc

3.8 (0.8)

3.7 (0.8)

3.7 (0.8)

 HDL cholesterol, mmol/Lc

1.3 (0.3)

1.5 (0.4)

1.5 (0.4)

 Triglycerides, mmol/Lc

2.4 (1.3)

1.7 (1.0)

1.7 (1.0)

 HbA1c, %

5.8 (0.4)

5.3 (0.3)

5.3 (0.3)

Previously diagnosed coronary heart disease, %

1.8

0.6

0.7

Parental history of diabetes, %

38

18

19

Mean fasting time (SD), hours

4.0 (2.6)

3.7 (2.4)

3.7 (2.4)

  1. Participants with missing data: total cholesterol, n = 7; LDL cholesterol n = 83
  2. BMI body mass index, DBP diastolic blood pressure, HC hip circumference, HDL high-density lipoprotein, LDL low-density lipoprotein, SBP systolic blood pressure, WC waist circumference, WHR waist-to-hip ratio
  3. aStandardised to age and sex structure of the study population
  4. bStandardised Townsend Deprivation Index; higher scores represent higher levels of deprivation
  5. cClinical chemistry derived concentrations