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Fig. 2 | BMC Medicine

Fig. 2

From: Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections

Fig. 2

Interactome network of the host-pathogen gene expression profiles derived from Dual RNA-seq of tissue biopsies of NSTI patients. The central column contains human genes, the left column contains S. pyogenes genes (i.e. bacterial genes found to be associated with human genes in monomicrobial NSTI), the right column contains genes from several bacterial species (i.e. bacterial genes found to be associated with human genes in polymicrobial NSTI). Nodes are colour coded by bacterial species; the node size is proportional to the node degree (connectivity, i.e. the number of associated genes; see Additional File 1, Equation S3). Red edges indicate positive partial correlation; blue edges indicate negative partial correlation; the colour intensity and the edge width are proportional to the magnitude of the partial correlations

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