Table 2 Validation of schizophrenia risk genes using independent integrative analysis method (SMR)
From: Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene
| Gene symbol | CHR | Top SNP | PGWAS | PeQTLa | PSMRb | Corrected PSMR |
|---|---|---|---|---|---|---|
| TYW5 | 2 | rs203772 | 1.83E-08 | 2.74E-10 | 1.90E-08 | <0.05 |
| CYP21A1P | 6 | rs2854275 | 2.26E-08 | 1.13E-10 | 2.60E-08 | <0.05 |
| C4A | 6 | rs1150752 | 4.05E-08 | 1.94E-17 | 4.55E-08 | <0.05 |
| BAG6 | 6 | rs707939 | 4.57E-08 | 4.70E-13 | 4.72E-08 | <0.05 |
| PCDHA10 | 5 | rs2240694 | 7.30E-14 | 3.05E-10 | 8.32E-14 | <0.05 |
| ITIH4 | 3 | rs6445539 | 6.21E-09 | 1.17E-09 | 6.59E-09 | <0.05 |
| DNM1P51 | 15 | rs12911210 | 9.24E-13 | 4.46E-13 | 1.07E-12 | <0.05 |
| BTN3A2 | 6 | rs1977 | 3.34E-14 | 5.30E-10 | 4.31E-14 | <0.05 |
| FTCDNL1 | 2 | rs13008446 | 8.04E-19 | 6.68E-01 | 1.07E-18 | <0.05 |
| MAPK3 | 16 | rs2005219 | 1.20E-09 | 9.61E-05 | 1.29E-09 | <0.05 |
| PCDHA9 | 5 | rs155799 | 1.90E-10 | 1.40E-04 | 2.06E-10 | <0.05 |