Fig. 1

Risk for mortality associated with individual diseases of interest at baseline. Cox proportional hazard regression models were used to examine the association between each of the 60 major diseases at baseline and incident mortality. Model 1 was adjusted for age and gender; Model 2 was adjusted for Model 1 plus ethnicity, education, income, BMI, smoking, physical acidity, alcohol consumption, sleep duration, diet, blood pressure, HDL-C, triglycerides, and HbA1c. Model 3 was adjusted for Model 2 plus all other 59 chronic diseases. The analysis for breast cancer, ovarian cancer, endometriosis, and polycystic ovary was conducted among women only while the analysis for prostate cancer and prostate disorders was conducted among men only. Individuals with disease diagnosed in the last year before mortality were excluded from the analysis. Horizontal lines indicate the ranges of the 95% CIs and the vertical dash lines indicate the hazard ratio of 1.0. *Refers to significant associations after adjustment for false discovery rate at a 5% level using Benjamin-Hochberg’s procedure