Fig. 4

RRs for efficacy (lower triangle) and safety (upper triangle) with their 95% CIs derived from network meta-analysis of 19 AF strategies in the full network colored by certainty of evidence assessed for each comparison with CINeMA and classified in high (in green), moderate (in blue), low (in yellow) and very low (in red). Empty cells correspond to comparisons not available for the safety outcome. RRs lower than 1 favor the treatment in the column for both outcomes. Abbreviations: Bi, bi-atrial; comb, combination; EGM, electrocardiogram; GP, ganglia plexi; mod, modification; LAA, left atrial appendage; RDN, renal denervation; RR, risk ratio; step, stepwise ablation; sub, substrate; SVC, superior vena cava; trig, trigger