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Fig. 2 | BMC Medicine

Fig. 2

From: Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants

Fig. 2

Multivariable regression and Mendelian randomization results for the risk of cardiovascular diseases associated with higher genetically predicted DHA and total omega-3 fatty acids among individuals of European ancestry. Results are expressed as odds ratio (OR) of cardiovascular diseases per standard unit increase in DHA and total omega-3 fatty acids with corresponding 95% confidence interval (CI). Full symbols indicate associations at P-value lower than the threshold accounting multiple testing (P < 0.006). Multivariable regression results are adjusted by for sex, age, BMI, fasting time, alcohol intake, frequency, statins use and total circulating fatty acids. DHA: docosahexaenoic acid; MV: multivariable regression; MR: Mendelian randomization; MVMR: multivariable Mendelian randomization; FA: fatty acids; TG: triglycerides; LDL: low-density lipoprotein cholesterol; ApoB: apolipoprotein B

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BMC Medicine

ISSN: 1741-7015

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