Fig. 3From: Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participantsMultivariable regression and Mendelian randomization results for the risk of cardiovascular diseases associated with higher genetically predicted linoleic acid and total omega-6 fatty acids among individuals of European ancestry. Results are expressed as odds ratio of cardiovascular diseases per standard unit increase in linoleic acid and total omega-6 fatty acids with corresponding 95% confidence interval (CI). Full symbols indicate associations at P-value lower than the threshold accounting multiple testing (P < 0.006). Multivariable regression results are adjusted by for sex, age, BMI, fasting time, alcohol intake, frequency, statins use and total circulating fatty acids. MV: multivariable regression; MR: Mendelian randomization; MVMR: multivariable Mendelian randomization; FA: fatty acids; TG: triglycerides; LDL: low-density lipoprotein cholesterol; ApoB: apolipoprotein BBack to article page