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Fig. 3 | BMC Medicine

Fig. 3

From: Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants

Fig. 3

Multivariable regression and Mendelian randomization results for the risk of cardiovascular diseases associated with higher genetically predicted linoleic acid and total omega-6 fatty acids among individuals of European ancestry. Results are expressed as odds ratio of cardiovascular diseases per standard unit increase in linoleic acid and total omega-6 fatty acids with corresponding 95% confidence interval (CI). Full symbols indicate associations at P-value lower than the threshold accounting multiple testing (P < 0.006). Multivariable regression results are adjusted by for sex, age, BMI, fasting time, alcohol intake, frequency, statins use and total circulating fatty acids. MV: multivariable regression; MR: Mendelian randomization; MVMR: multivariable Mendelian randomization; FA: fatty acids; TG: triglycerides; LDL: low-density lipoprotein cholesterol; ApoB: apolipoprotein B

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