Fig. 4From: Biological aging mediates the associations between urinary metals and osteoarthritis among U.S. adultsEstimated proportion of the association between urinary mixed metals and OA mediated by biological age (A), phenotypic age (B), and telomere length (C) and serially mediated by telomere length-biological age path (D) and telomere length-phenotypic age path (E). Models were adjusted for sex, age, race/ethnicity, education, family income-to-poverty ratio, marital status, body mass index, physical activity, drinking alcohol status, and serum cotinine. IE, the estimate of the indirect effect; DE, the estimate of the direct effect; Proportion of mediation = IE/DE + IEBack to article page