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Table 2 Associations of aging makers with OA risk, NHANES 1999–2016

From: Biological aging mediates the associations between urinary metals and osteoarthritis among U.S. adults

  Continuous Q1 Q2 Q3 Q4 P for trend
  OR (95% CI)   OR (95% CI) OR (95% CI) OR (95% CI)  
Biological age 1.06 (1.05, 1.07) 1.00 (reference) 4.32 (1.90, 9.84) 15.1 (6.69, 34.07) 16.75 (7.46, 37.64)  < 0.001
Phenotypic age 1.04 (1.04, 1.05) 1.00 (reference) 6.48 (2.74, 15.31) 18.78 (8.03, 43.93) 22.91 (9.31, 56.37)  < 0.001
Telomere length 0.26 (0.07, 0.97) 1.00 (reference) 0.76 (0.37, 1.54) 0.58 (0.30, 1.11) 0.40 (0.17, 0.90) 0.022
  1. Models were adjusted for sex, age, race/ethnicity, education, family income-to-poverty ratio, marital status, body mass index, physical activity, drinking alcohol status, and serum cotinine. Q, quartile. All P for trend were FDR-adjusted