Placenta-derived proteins across gestation in healthy pregnancies—a novel approach to assess placental function?

Table 2 Demographic and clinical characteristics of the 4-vessel and the STORK cohort

	4-vessel (n = 75)					STORK (n = 70)
	n	%	Mean (SD)	Min	Max	n	%	Mean (SD)	Min	Max
Mothers
Age (years)			36.0 (3.8)	28.0	44.0			32.1 (3.6)	24	41
Pre-pregnancy BMI^a (kg/m²)			23.7 (4.8)^e	17.0	47.6			24.1 (2.9)	18.5	31.1
Systolic blood pressure (mmHg)^b			109.9 (10.7)	90	135			110.0 (9.7)	90	130
Diastolic blood pressure (mmHg)^b			68.1 (8.6)	48.0	83.0			66.3 (8.1)	45	80
No smoking during pregnancy^c	71	94.7				69	98.5
Higher education^d	66	88.0				58	82.9
Married/partner	71	94.7				70	100.0
Nulliparity	17	22.7				35	50.0
GA, 1st sampling								15.7 (1.2)^e	12.1	18.1
GA, 2nd sampling								23.4 (1.0)	21.6	26.4
GA, 3rd sampling								31.3 (1.0)	29.4	33.6
Infants
Sex (boys)	43	57.3				40	57.0
GA at birth			38.8 (0.6)	37.0	41.0			40.3 (1.2)	37.6	42.6
Placental weight (g)			617.7 (124.7)	310.0	900.0			699.2 (147.5) ^e	470	1030
Birthweight (g)			3579.2 (424.4)	2297.0	4520.0			3549.5 (463.2)	2325	4760

GA gestational age in weeks
^a4-vessel: based on self-reported pre-pregnancy weight and height, STORK: based on measured weight and height at first visit
^bFirst trimester measurement
^c4-vessel: no smoking during pregnancy vs. stopped smoking in first trimester. No women continued smoking once they were aware of their pregnancy, STORK: self-reported “no smoking during pregnancy” vs. “smoking”
^dUniversity college/university education (> 15 years)
^eMissing data: 4 vessel cohort: pre-pregnancy BMI n = 72; STORK cohort: GA 1st sampling n = 64, placental weight n = 66

ISSN: 1741-7015