Table 3 Placental release and uptake. The ten proteins with the smallest FDR adjusted p-values

Proteins released by the placenta to the maternal circulation

% higher RFU in uterine vein

 Pleiotrophin

PTN

7.57E−17

33.68

 Fatty-acid amide hydrolase 2

FAAH2

2.90E−16

97.85

 Secreted frizzled-related protein 3

FRZB

2.90E−16

56.58

 Secreted frizzled-related protein 1

SFRP1

2.90E−16

22.62

 Signal peptide, CUB and EGF-like domain-containing protein 3

SCUBE3

4.08E−16

23.77

 Placenta growth factor

PGF

1.17E−15

76.17

 Urokinase-type plasminogen activator

PLAU

2.68E−14

55.37

 Tubulin polymerization-promoting protein family member 2

TPPP2

2.49E−13

32.90

 Noggin

NOG

2.49E−13

14.44

 Transgelin

TAGLN

8.36E−13

38.39

Proteins taken up by the placenta from the maternal circulation

% lower RFU in uterine vein

 Beta-defensin 1

DEFB1

3.14E−11

14.51

 Insulin

INS

3.06E−07

6.53

 Parathyroid hormone

PTH

5.95E−07

9.92

 Urokinase plasminogen activator surface receptor

PLAUR

2.13E−06

6.19

 Corticotropin-releasing factor-binding protein

CRHBP

7.53E−05

5.60

 Trefoil factor 2

TFF2

8.12E−05

5.41

 Vascular endothelial growth factor A, isoform 121

VEGFA

1.11E−04

4.19

 Trefoil factor 1

TFF1

1.89E−04

6.09

 Steroidogenic acute regulatory protein, mitochondrial

STAR

2.10E−04

6.25

 Complexin-2

CPLX2

2.40E−04

3.05