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Table 4 Incidence rates of rheumatoid arthritis according to different time intervals and seropositivity

From: A positive faecal immunochemical test result and its association with the incidence of rheumatoid arthritis, systemic lupus erythematosus, and psoriatic arthritis: an analysis of one-million national colorectal cancer screening programme results

Groups

Total number

IR (95% CI)

Adjusted IR (95% CI)a

<1 year

1–5 years

≥5 years

<1 year

1–5 years

≥5 years

<1 year

1–5 years

≥5 years

Overall (n=7645)

 Overall

1359

4173

2113

13.06 (12.38, 13.77)

8.21 (7.97, 8.46)

2.70 (2.59, 2.82)

-

-

-

 FIT (-) group (Ref.)

1038

3113

1583

12.78 (12.03, 13.59)

7.87 (7.59, 8.15)

2.62 (2.50, 2.75)

11.89 (10.56, 13.38)

7.56 (6.85, 8.33)

2.60 (2.37, 2.86)

 FIT (+) Group

321

1060

530

14.02 (12.57, 15.64)

9.43 (8.88, 10.01)

2.97 (2.72, 3.23)

13.27 (11.79, 14.93)

8.88 (8.06, 9.80)

2.92 (2.65, 3.21)

 p value

   

0.948

0.898

0.931

0.196

0.022

0.094

Seropositive RA (n=3184)

 Overall

553

1715

916

5.31 (4.89, 5.77)

3.37 (3.21, 3.53)

1.17 (1.09, 1.24)

-

-

-

 FIT (−) group (Ref.)

428

1287

698

5.27 (4.80, 5.80)

3.25 (3.07, 3.43)

1.15 (1.07, 1.24)

4.94 (3.77, 6.47)

3.16 (2.84, 3.52)

1.15 (1.06, 1.25)

 FIT (+) Group

125

428

218

5.46 (4.58, 6.51)

3.80 (3.45, 4.18)

1.21 (1.06, 1.39)

5.44 (4.15, 7.13)

3.64 (3.27, 4.06)

1.20 (1.10, 1.31)

 p value

   

0.980

0.912

0.970

0.622

0.069

0.457

Seronegative RA (n=4461)

 Overall

806

2458

1197

7.74 (7.23, 8.30)

4.83 (4.64, 5.03)

1.53 (1.44, 1.61)

-

-

-

 FIT (−) group (Ref.)

610

1826

885

7.51 (6.94, 8.13)

4.61 (4.40, 4.82)

1.46 (1.37, 1.56)

7.04 (6.01, 8.26)

4.39 (3.91, 4.93)

1.45 (1.27, 1.65)

 FIT (+) Group

196

632

312

8.56 (7.44, 9.85)

5.61 (5.19, 6.07)

1.74 (1.56, 1.95)

7.51 (6.40, 8.80)

5.19 (4.62, 5.83)

1.70 (1.49, 1.93)

 p value

   

0.927

0.889

0.902

0.581

0.046

0.087

  1. RA rheumatoid arthritis, IR incidence rate per 10,000 person-years, CI confidence interval, FIT faecal immunochemical test
  2. aAge and sex adjusted