Table 7 Baseline characteristics after propensity-score matching
|  | Total cohort n=437,250 | FIT (−) n=291,500a | FIT (+) n=145,750a | p value | SMD |
|---|---|---|---|---|---|
Clinical parameter | |||||
 Sex |  |  |  | 0.227 | 0.0033 |
  Male | 246,455 (56.4) | 164,490 (56.4) | 81,965 (56.2) |  |  |
  Female | 190,795 (43.6) | 127,010 (43.6) | 63,785 (43.8) |  |  |
 Age group at screening, years |  |  |  | 0.738 | <0.001 |
  50–54 | 131,325 (30.0) | 87,635 (30.1) | 43,690 (30.0) |  |  |
  55–59 | 92,338 (21.1) | 61,530 (21.1) | 30,808 (21.1) |  |  |
  60–64 | 92,705 (21.2) | 61,699 (21.2) | 31,006 (21.3) |  |  |
  65–69 | 57,884 (13.2) | 38,527 (13.2) | 19,357 (13.3) |  |  |
  ≥70 | 62,998 (14.4) | 42,109 (14.4) | 20,889 (14.3) |  |  |
 BMI, kg/m2 | 24.1 [22.2, 26.1] | 24.1 [22.1, 26.1] | 24.1 [22.3, 26.1] | 0.896 | 0.003 |
 Smoking status |  |  |  | 0.744 | 0.001 |
  No | 367,195 (84.0) | 244,834 (84.0) | 122,361 (84.0) |  |  |
  Yes | 70,055 (16.0) | 46,666 (16.0) | 23,389 (16.0) |  |  |
 Alcohol drinking |  |  |  | 0.541 | 0.002 |
  No | 340,638 (77.9) | 227,013 (77.9) | 113,625 (78.0) |  |  |
  Yes | 96,612 (22.1) | 64,487 (22.1) | 32,125 (22.0) |  |  |
 Exercise |  |  |  | 0.790 | <0.001 |
  No | 134,288 (30.7) | 89,487 (30.7) | 44,801 (30.7) |  |  |
  Yes | 302,962 (69.3) | 202,013 (69.3) | 100,949 (69.3) |  |  |
 Insurance type |  |  |  | 0.223 | <0.001 |
  Medical aid | 2,336 (0.5) | 1,585 (0.5) | 751 (0.5) |  |  |
  NHI | 434,914 (99.5) | 289,915 (99.5) | 144,999 (99.5) |  |  |
 Comorbidities |  |  |  |  |  |
  Hypertension |  |  |  | 0.657 | 0.001 |
   No | 390,814 (89.4) | 260,500 (89.4) | 130,314 (89.4) |  |  |
   Yes | 46,436 (10.6) | 31,000 (10.6) | 15,436 (10.6) |  |  |
  Diabetes |  |  |  | 0.709 | 0.001 |
   No | 410,481 (93.9) | 273,626 (93.9) | 136,855 (93.9) |  |  |
   Yes | 26,769 (6.1) | 17,874 (6.1) | 8,895 (6.1) |  |  |
  Dyslipidaemia |  |  |  | 0.402 | 0.003 |
  No | 310,009 (70.9) | 206,554 (70.9) | 103,455 (71.0) |  |  |
  Yes | 127,241 (29.1) | 84,946 (29.1) | 42,295 (29.0) |  |  |
Laboratory measures | |||||
 Blood haemoglobin, g/dL | 13.8 [12.8,14.9] | 13.8 [12.8,14.9] | 13.8 [12.8,14.9] | 0.002 | 0.001 |
 Serum creatinine, mg/dL | 0.9 [0.8,1.0] | 0.9 [0.8,1.0] | 0.9 [0.8,1.0] | <0.001 | 0.005 |
 Serum total cholesterol, mg/dL | 198 [174,224] | 198 [174,224] | 198 [174,224] | 0.304 | 0.004 |
 Serum triglycerides, mg/dL | 116 [81,167] | 116 [82,166] | 16 [81,167] | 0.318 | <0.001 |
 Serum HDL-cholesterol, mg/dL | 52 [44,61] | 52 [44,61] | 52 [44,62] | <0.001 | <0.001 |
 Serum LDL-cholesterol, mg/dL | 118 [95,142] | 118 [95,142] | 18 [95,142] | 0.058 | 0.003 |