Table 2 Presentation characteristics of patients with first ST-segment elevation myocardial infarction by number of cardiovascular risk factors
Variables | Total (N = 16228) | No SMuRF (N = 1918) | 1–2 SMuRFs (N = 11503) | 3–4 SMuRFs (N = 2807) | P value |
|---|---|---|---|---|---|
Presentation characteristics | |||||
 Emergency medical system | 1736 (10.7) | 186 (9.7) | 1204 (10.5) | 346 (12.4) | 0.0009 |
 Onset-to-arrival time |  |  |  |  | <0.0001 |
  <3 h | 3844 (23.9) | 392 (20.7) | 2681 (23.5) | 771 (27.6) |  |
  3–12 h | 6974 (43.3) | 811 (42.9) | 4965 (43.5) | 1198 (42.9) |  |
  12–24 h | 1665 (10.3) | 197 (10.4) | 1190 (10.4) | 278 (10.0) |  |
  1–7 d | 3619 (22.5) | 491 (26.0) | 2584 (22.6) | 544 (19.5) |  |
 Time for symptoms to first medical contact, minute | 328 (139–1124) | 370 (165–1441) | 330 (140–1115) | 300 (120–1005) | 0.0001 |
 GRACE risk score | 148.4±35.4 | 156.1±35.7 | 148.5±34.9 | 143.1±36.5 | <0.0001 |
 Systolic blood pressure, mmHg | 127.3±24.9 | 120.5±22.1 | 127.1±24.5 | 133.1±27.0 | <0.0001 |
 Heart rate, beats/min | 77.4±18.1 | 76.8±18.0 | 77.2±18.0 | 78.9±18.6 | <0.0001 |
 Cardiac arrest at presentation | 207 (1.3) | 24 (1.3) | 144 (1.3) | 39 (1.4) | 0.84 |
 Killip class |  |  |  |  | 0.21 |
  I | 12466 (77.2) | 1484 (77.7) | 8846 (77.2) | 2136 (76.4) |  |
  II | 2510 (15.5) | 276 (14.5) | 1805 (15.8) | 429 (15.3) |  |
  III | 566 (3.5) | 68 (3.6) | 385 (3.4) | 113 (4.0) |  |
  IV | 615 (3.8) | 81 (4.2) | 416 (3.6) | 118 (4.2) |  |
 LVEF |  |  |  |  | 0.06 |
  Normal, >50% | 8633 (68.5) | 899 (66.2) | 6172 (68.6) | 1562 (69.1) |  |
  Slightly, 40–49% | 3050 (24.2) | 340 (25.0) | 2193 (24.4) | 517 (22.9) |  |
  Moderately, 30–39% | 797 (6.3) | 99 (7.3) | 546 (6.1) | 152 (6.7) |  |
  Severely, <30% | 132 (1.0) | 21 (1.5) | 83 (0.9) | 28 (1.2) |  |
 Anterior myocardial infarction | 9091 (56.2) | 1121 (58.6) | 6431 (56.1) | 1539 (55.0) | 0.048 |
 Three-vessel coronary artery diseasea | 3762 (36.4) | 300 (29.2) | 2624 (35.9) | 838 (41.9) | <0.0001 |
Laboratory variables | |||||
 Creatinine, mmol/L | 74.0 (61.7–90.0) | 71.0 (59.0–87.0) | 74.0 (62.0–90.0) | 75.5 (62.0–91.0) | <0.0001 |
 Glucose, mmol/L | 7.0 (5.7–9.1) | 6.4 (5.4–7.6) | 6.8 (5.6–8.7) | 9.2 (6.8–12.8) | <0.0001 |
 Glycated hemoglobin A1c, % | 6.0 (5.5–7.0) | 5.6 (5.3–6.0) | 5.9 (5.5–6.5) | 6.9 (6.0–8.3) | <0.0001 |
 Total cholesterol, mmol/L | 4.5 (3.8–5.3) | 4.1 (3.6–4.6) | 4.5 (3.8–5.2) | 5.3 (4.4–5.9) | <0.0001 |
 Triglycerides, mmol/L | 1.4 (1.0–2.0) | 1.1 (0.8–1.6) | 1.4 (1.0–2.0) | 1.7 (1.2–2.6) | <0.0001 |
 LDL cholesterol, mmol/L | 2.8 (2.2–3.4) | 2.4 (2.0–2.8) | 2.7 (2.2–3.3) | 3.4 (2.6–3.8) | <0.0001 |
 HDL cholesterol, mmol/L | 1.1 (0.9–1.3) | 1.1 (0.9–1.3) | 1.1 (0.9–1.3) | 1.1 (0.9–1.3) | 0.16 |