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Table 3 Medical management and in-hospital outcomes of patients with first ST-segment elevation myocardial infarction by number of cardiovascular risk factors

From: Number of standard modifiable risk factors and mortality in patients with first-presentation ST-segment elevation myocardial infarction: insights from China Acute Myocardial Infarction registry

Variables

Total (N = 16228)

No SMuRF (N = 1918)

1–2 SMuRFs (N = 11503)

3–4 SMuRFs (N = 2807)

P value

In-hospital management

 Reperfusion therapy

     

 Among all the patients

    

<0.0001

  No reperfusion

7430 (46.2)

1000 (52.8)

5323 (46.7)

1107 (39.8)

 

  Fibrinolysis

1618 (10.1)

172 (9.1)

1173 (10.3)

273 (9.8)

 

  Primary PCI

7017 (43.7)

722 (38.1)

4894 (43.0)

1401 (50.4)

 

 Among patients admitted within 12 h from onset

    

<0.0001

  No reperfusion

2953 (27.6)

394 (33.2)

2118 (28.0)

441 (22.6)

 

  Fibrinolysis

1552 (14.5)

163 (13.7)

1122 (14.8)

267 (13.7)

 

  Primary PCI

6210 (58.0)

631 (53.1)

4336 (57.2)

1243 (63.7)

 

 Door-to-balloon time, minute

107 (75–159)

110 (63–200)

107 (75–158)

105 (75–150)

0.75

 Door-to needle time, minute

53 (30–90)

50 (29–80)

55 (30–90)

50 (30–101)

0.30

 Any PCI

10361 (63.8)

1041 (54.3)

7342 (63.8)

1978 (70.5)

<0.0001

 Any CABG

98 (0.6)

9 (0.5)

65 (0.6)

24 (0.9)

0.15

 Intra-aortic balloon pump use

547 (3.4)

50 (2.6)

374 (3.3)

123 (4.4)

0.002

Medication during hospitalization

 Aspirin

15697 (97.1)

1840 (96.6)

11119 (97.0)

2738 (97.8)

0.03

 P2Y12-receptor inhibitor

15669 (97.5)

1811 (95.7)

11128 (97.7)

2730 (98.1)

<0.0001

 Statin

15598 (96.8)

1807 (95.6)

11076 (96.9)

2715 (97.2)

0.006

 β-blocker

11227 (70.0)

1270 (67.2)

7935 (69.7)

2022 (73.4)

<0.0001

 ACEI/ARB

9404 (58.7)

914 (48.5)

6619 (58.2)

1871 (67.9)

<0.0001

 Heparin

14449 (91.5)

1642 (88.8)

10288 (91.8)

2519 (92.2)

<0.0001

 Glucoprotein IIb or IIIa inhibitor

5511 (35.3)

549 (30.0)

3920 (35.3)

1042 (38.5)

<0.0001

In-hospital outcome

 Death

1015 (6.3)

157 (8.2)

702 (6.1)

156 (5.6)

0.0006

 Cardiac arrest

567 (3.5)

90 (4.8)

394 (3.5)

83 (3.0)

0.004

 Heart failure

2501 (15.6)

311 (16.5)

1778 (15.6)

412 (14.8)

0.31

 Re-infarction

88 (0.5)

8 (0.4)

62 (0.5)

18 (0.6)

0.59

 Cerebrovascular accident or stroke

127 (0.8)

12 (0.6)

92 (0.8)

23 (0.8)

0.72

 Severe arrhythmia

1372 (8.5)

161 (8.5)

1005 (8.8)

206 (7.4)

0.06

 Length of stay, day

10 (7–13)

10 (7–14)

10 (7–13)

9 (7–13)

0.04

Medication at dischargea

 Aspirin

15066 (99.2)

1726 (98.3)

10706 (99.3)

2634 (99.4)

<0.0001

 Clopidogrel

14868 (98.0)

1701 (97.1)

10567 (98.0)

2600 (98.2)

0.03

 Statin

14993 (98.7)

1709 (97.5)

10664 (98.9)

2620 (98.9)

<0.0001

 β-blocker

11725 (77.3)

1319 (75.2)

8279 (76.9)

2127 (80.5)

<0.0001

 ACEI/ARB

10135 (66.8)

1014 (57.9)

7131 (66.2)

1990 (75.3)

<0.0001

  1. SMuRF standard modifiable cardiovascular risk factor, PCI Percutaneous coronary intervention, CABG Coronary artery bypass graft, ACEI Angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker
  2. aMedication at discharge was described after removing patients with in-hospital deaths