Fig. 5From: Risk and benefit for umbrella trials in oncology: a systematic review and meta-analysisForest plot of proportions of treatment-related grade 3/4 AEs in experimental sub-trials included in the meta-analysis (random effects). The analysis included data from 5 experimental sub-trials/arms with a total of 91 patients that experienced drug-related grade 3/4 AEs. AEs, adverse events; CI, confidence intervalBack to article page