Fig. 7From: Risk and benefit for umbrella trials in oncology: a systematic review and meta-analysisForest plot of proportions of treatment-related grade 5 AEs in 17 sub-trials/arms included in the meta-analysis (random effects). The analysis included data from 17 sub-trials/arms with a total of 12 drug-related deaths among 1233 participants evaluated for toxicity. AEs, adverse events; CI, confidence intervalBack to article page