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Fig. 4 | BMC Medicine

Fig. 4

From: Combined associations of family history and self-management with age at diagnosis and cardiometabolic risk in 86,931 patients with type 2 diabetes: Joint Asia Diabetes Evaluation (JADE) Register from 11 countries

Fig. 4

Kaplan-Meier estimate of age at diagnosis stratified by combination of family history and healthy lifestyles. FamH, family history of diabetes (father, mother, and/or siblings). Healthy lifestyles include adequate physical activity (30 min at least 3 times weekly), adherence to a balanced diet, never or occasional alcohol drinker, and never or ex-smoker. The figure shows the mean age at diagnosis (years) in FamH- group with <2 healthy lifestyles vs. FamH− group with ≥2 healthy lifestyles vs. FamH+ group with <2 healthy lifestyles vs. FamH+ group with ≥2 healthy lifestyles in (A) overall study population [50.1, 95%CI 49.8–50.5] vs. [52.8, 95%CI 52.7–52.9] vs. [46.0, 95%CI 45.8–46.2] vs. [48.2, 95%CI 48.1–48.3], (B) China [53.0, 95%CI 51.5–54.5] vs. [57.4, 95%CI 56.3–58.4] vs. [50.2, 95%CI 48.6–51.8] vs. [54.3, 95%CI 53.1–55.4], (C) Hong Kong [56.0, 95%CI 54.4–57.6] vs. [59.5, 95%CI 58.7–60.2] vs. [52.0, 95%CI 51.1–53.0] vs. [54.5, 95%CI 54.0–55.0], (D) India [51.5, 95%CI 49.5–53.5] vs. [52.9, 95%CI 52.3–53.5] vs. [46.0, 95%CI 45.2–46.9] vs. [48.5, 95%CI 48.0–48.9], (E) Indonesia [52.8, 95%CI 47.9–57.6] vs. [58.8, 95%CI 56.6–60.9] vs. [50.2, 95%CI 45.6–54.8] vs. [58.0, 95%CI 55.5–60.4], (F) Korea [50.9, 95%CI 45.7–56.1] vs. [55.3, 95%CI 51.6–59.0] vs. [50.3, 95%CI 45.3–55.2] vs. [53.1, 95%CI 50.4–55.7], (G) Malaysia [52.4, 95%CI 47.1–57.7] vs. [53.2, 95%CI 51.6–54.8] vs. [45.7, 95%CI 43.8–47.6] vs. [48.2, 95%CI 47.5–48.9], (H) Philippines [53.7, 95%CI 51.8–55.6] vs. [58.6, 95%CI 57.7–59.5] vs. [51.6, 95%CI 49.9–53.2] vs. [53.7, 95%CI 52.9-54.5], (I) Singapore [53.0, 95%CI 53.0–53.0] vs. [59.4, 95%CI 54.4–64.4] vs. [53.3, 95%CI 49.2–57.3] vs. [55.2, 95%CI 52.5-57.9], (J) Taiwan [53, 95%CI 53–53] vs. [59.4, 95%CI 54.4–64.4] vs. [53.3, 95%CI 49.2–57.3] vs. [55.2, 95%CI 52.5-57.9], (K) Thailand [58.1, 95%CI 55.0–61.3] vs. [45.0, 95%CI 40.4–49.6] vs. [59.8, 95%CI 53.4–66.2] vs. [57.2, 95%CI 54.3–60.0], and (L) Vietnam [54.5, 95%CI 51.7–57.4] vs. [58.5, 95%CI 57.3–59.6] vs. [50.7, 95%CI 47.2–54.2] vs. [52.8, 95%CI 51.5–54.1]. All comparisons showed p <0.05 with log-rank test

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