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Table 1 Summary characteristics of studies (N = 59)

From: Costs of multimorbidity: a systematic review and meta-analyses

Study characteristic

Articles n (%)

Type of study (N = 59)

 Cross-sectional

32 (54%)

 Cohort/longitudinal

26 (44%)

 Case-control

1 (2%)

World Bank classification (n = 59)

 High-income country

56 (95%)

 Middle-income country

3 (5%)

 Low-income country

0 (0)

Source of data (n = 59)*

 Insurance claim database

37 (63%)

 Hospital/medical database

19 (32%)

 Patient survey

20 (34%)

 Linked database

20 (34%)

 Other

6 (10%)

Type of costs included (n = 59)*

 Direct medical costs

58 (98%)

 Direct non-medical costs

2 (3%)

 Indirect costs

7 (12%)

Costing perspective (n = 59)*

 Public

48 (81%)

 Household/patient

12 (20%)

 Societal

8 (14%)

 Provider

1 (2%)

Number of disease combination sets from all studies* (n = 325)

 Included in narrative synthesis (research questions 1 and 4)

229 (70%)

 Included in country comparison (research question 2)

41 (13%)

 Included in meta-analyses (research question 3)

34 (10%)

Number of conditions in each disease combination set (n = 325)

 Two

282 (87%)

 More than two

43 (13%)

Frequently appeared in disease combination sets* (n = 325)

 Diabetes

96 (30%)

 Heart/vascular conditions

93 (29%)

 Mental health conditions

67 (21%)

 Hypertension

59 (18%)

 Respiratory conditions

52 (16%)

 Cancers

38 (12%)

Quality score

Mean

 Cross-sectional studies (n = 32)

7.8 out of 10

 Cohort studies (n = 26)

7.9 out of 9

 Case-control studies (n = 1)

7.0 out of 9

  1. *Studies can belong to more than one category, meaning individual percentages at times do not sum to 100%