Table 1 Definitions and descriptions for identification of acute kidney injury (AKI) episode

 Reference value 1 (RV₁)

Lowest value of:

• Median of the SCr levels in the 8 to 365 days prior to the index date

• Lowest of the SCr levels in the 1 to 7 days prior to the index date

 Reference value 2 (RV₂)

Lowest value of the SCr levels in the 1 to 2 days (48 h) prior to the index date

 By SCr ratio

Index SCr ≥ 1.5 times higher than RV₁

 By SCr increment

Index SCr <  1.5 times higher than RV₁; but ≥26.5 μmol/L higher than RV₂

 Stage 1

Index SCr/RV₁ ≥ 1.5 and <  2; or Index SCr – RV₂ ≥ 26.5 μmol/L

 Stage 2

Index SCr/RV₁ ≥ 2 and <  3

 Stage 3

Index SCr/RV₁ ≥ 3; or Index SCr ≥ 353.6 μmol/L

 Community-acquired/community-managed AKI

AKI diagnosed in the community and not admitted to hospital within 7 days

 Community-acquired/hospital-managed AKI

Either of the following:

• AKI developed in the community and admitted to hospital within 7 days

• AKI presented in the first 2 days in hospital, i.e. day 0 (admission) + day 1

 Hospital-acquired AKI

AKI developed on or after 2 days in hospital, i.e. from day 2 onwards

 Creatinine-recovery

Patient recovered, did not die and did not initiate chronic KRT during the period considered

 No creatinine-recovery

Patient did not recover, did not die and did not initiate chronic KRT during the period considered

 Death

Patient died during the period considered

 KRT

Patient initiated KRT during the period considered

 Untested

Patient was not tested, did not die and did not initiate chronic KRT during the period considered