Weight loss-induced improvement of body weight and insulin sensitivity is not amplified by a subsequent 12-month weight maintenance intervention but is predicted by adaption of adipose atrial natriuretic peptide system: 48-month results of a randomized controlled trial

Table 3 Change of SF-36-based physical component summary (PCS) score and mental component summary (MCS) score [mean and 95% CI] compared to baseline within the per-protocol analysis. Changes were reported as estimated mean differences based on a mixed-model, repeated-measures analysis of variance adjusted for the treatment group, sex, age, and BMI at baseline

Months after weight loss	Change of PCS compared to baseline	Change of MCS compared to baseline
0	5.53 [3.71, 7.34]	3.70 [1.79, 5.60]
12	4.96 [2.84, 7.08]	2.25 [0.09, 4.42]
18	3.82 [1.78, 5.86]	2.06 [-0.08, 4.20]
24	3.11 [1.10, 5.12]	2.00 [-0.28, 4.18]
36	3.18 [1.12, 5.25]	1.73 [-0.89, 4.34]
48	2.95 [0.49, 5.40]	1.79 [-1.00, 4.58]

ISSN: 1741-7015