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Table 5 Independent association of NPR-A after weight loss and male sex with an increase of HOMA-IR at month 48 (ΔHOMA-IRT0T48). Stepwise multiple linear regression analysis was adjusted for the treatment group, age, sex, HOMA-IR after weight loss, and ΔBMIT0T48. Male sex was defined as 1 and female sex was defined as 2

From: Weight loss-induced improvement of body weight and insulin sensitivity is not amplified by a subsequent 12-month weight maintenance intervention but is predicted by adaption of adipose atrial natriuretic peptide system: 48-month results of a randomized controlled trial

Predictors

Coefficients

Standard error

Standardized β

R2

Adipose NPR-A mRNA

−0.001

3.5×10-4

−0.422*

0.361**

Sex

−1.669

0.650

−0.438*

  1. NPR natriuretic receptor
  2. *p<0.05
  3. **p<0.01
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BMC Medicine

ISSN: 1741-7015

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