The association between the pre-pregnancy vaginal microbiome and time-to-pregnancy: a Chinese pregnancy-planning cohort study

Table 2 Fecundability ratios for different vaginal microbiome types

Type	N (%)	Crude FR (95%CI)	Model A, FR (95%CI)	Model B, FR (95%CI)
A	82 (24.7)	Ref	Ref	Ref
B	43 (13.0)	0.75 [0.45, 1.26]	0.84 [0.48, 1.46]	0.86 [0.49, 1.50]
C	67 (20.2)	0.70 [0.44, 1.12]	0.81 [0.51, 1.30]	0.82 [0.51, 1.31]
D	74 (22.3)	0.41 [0.24, 0.68]*	0.45 [0.26, 0.76]*	0.45 [0.27, 0.77]*
E	66 (19.9)	0.70 [0.44, 1.11]	0.71 [0.44, 1.15]	0.71 [0.44, 1.14]

Model A: TTP was determined by month. FRs were adjusted for female age, the age difference between couples, educational level, occupation, pregnancy history, and vaginal cleanliness grading
Model B: TTP was determined by the menstrual cycle. FRs were adjusted for female age, the age difference between couples, educational level, occupation, pregnancy history, and vaginal cleanliness grading
*The FR is statistically significant

ISSN: 1741-7015