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Table 3 Results of model estimating change in % FMD at 3- and 6-month follow-ups of cessation subgroup (upper section) and changes in means (difference over baseline) in %FMD for the cessation subgroup for 3- and 6-month follow-ups (lower section)

From: Medium- and longer-term cardiovascular effects of e-cigarettes in adults making a stop-smoking attempt: a randomized controlled trial

Variables

Group/follow-up

B-coeff

Exp (B)

95% CI

p value

Lower

Upper

%FMD

Group

NRT over EC nicotine-containing

0.46

1.61

− 0.59

1.54

0.38

EC nicotine-free over EC nicotine-containing

− 0.57

0.57

− 1.74

0.60

0.34

Follow-up

3 m over baseline

2.40

20.04

1.66

3.14

< 0.0001

6 m over baseline

2.99

11.04

2.22

3.77

< 0.0001

Gender

Male over female

− 1.35

0.26

− 2.27

− 0.43

0.004

Age

− 0.02

0.98

− 0.05

0.01

0.27

Intercept

7.67

 

5.92

9.42

< 0.0001

%FMD changes over baseline

NRT

EC—nicotine-containing

EC – nicotine-free

Mean difference

95% CI

p value

Mean difference

95% CI

p value

Mean difference

95% CI

p value

Lower

Upper

Lower

Upper

Lower

Upper

3 months over baseline

Cessation subgroup

2.61

0.97

4.25

0.003

3.94

1.73

6.15

0.001

4.78

2.27

7.29

0.001

6 months over baseline

Cessation subgroup

4.40

2.18

6.66

0.001

2.96

1.17

4.74

0.002

2.97

0.90

5.04

0.006

  1. %FMD, percentage change in flow-mediated dilation