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Table 4 Quality of life by domain at baseline, 3 and 6 months follow-ups of all participants

From: Medium- and longer-term cardiovascular effects of e-cigarettes in adults making a stop-smoking attempt: a randomized controlled trial

Baseline, 3 and 6 months, mean

Nicotine replacement therapy

Nicotine-containing e-cigarettes

Nicotine-free e-cigarettes

F value, p value, and degrees of freedom

Mobility (%)

Baseline

9.88

15.48

13.92

F = 0.60, p = 0.55, df = 2,243

3 months

7.41

9.52

10.13

F = 0.20, p = 0.82, df = 2,243

6 months

6.17

7.14

8.86

F = 0.21, p = 0.81, df = 2,243

Self-care (%)

Baseline

2.47

5.95

3.80

F = 0.65, p = 0.52, df = 2,243

3 months

2.47

2.38

1.27

F = 0.12, p = 0.84, df = 2,243

6 months

1.23

3.57

2.53

F = 0.20, p = 0.82, df = 2,243

Usual activity (%)

Baseline

8.64

16.67

18.99

F = 1.89, p = 0.15, df = 2,243

3 months

7.41

14.29

12.66

F = 1.04, p = 0.36, df = 2,243

6 months

6.17

15.48

10.13

F = 1.90, p = 0.15, df = 2,243

Pain (%)

Baseline

35.80

39.29

46.84

F = 1.05, p = 0.35, df = 2,243

3 months

23.46

25.00

29.11

F = 0.35, p = 0.70, df = 2,243

6 months

17.28

21.43

34.18

F = 3.43, p = 0.03, df = 2,243

Depression/anxiety (%)

Baseline

38.27

45.24

51.90

F = 1.50, p = 0.22, df = 2,243

3 months

23.46

42.86

43.04

F = 4.54, p = 0.01, df = 2,243

6 months

24.69

50.00

44.30

F = 6.25, p = 0.01, df = 2,243

QALY (%)

Baseline

41.98

34.52

32.91

F = 0.81, p = 0.45, df = 2,243

3 months

62.96

44.05

43.04

F = 4.17, p = 0.02, df = 2,243

6 months

64.20

42.86

43.04

F = 5.03, p = 0.01, df = 2,243

VAS (Mean, SD)

Baseline, mean (SD)

71.59 (15.98)

67.26 (15.24)

70.96 (17.14)

F = 1.74, p = 0.18, df = 2,243

3 months, mean (SD)

72.38 (14.33)

70.91 (14.42)

69.81 (19.24)

F = 0.51, p = 0.60, df = 2,243

6 months, mean (SD)

75.38 (13.80)

70.29 (16.12)

72.78 (16.22)

F = 2.24, p = 0.11, df = 2,243