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Table 5 Change of secondary outcome variables over baseline

From: Medium- and longer-term cardiovascular effects of e-cigarettes in adults making a stop-smoking attempt: a randomized controlled trial

Variables—change over baseline Nicotine replacement therapy (NRT) Nicotine-containing e-cigarettes Nicotine-free e-cigarettes
Mean difference 95% CI p value Mean difference 95% CI p value Mean difference 95% CI p value
Lower Upper Lower Upper Lower Upper
CO (reduction in parts per million)
3 months over baseline 10 8 11  < .001 9 7 11 < .001 7 5 9 < .001
6 months over baseline 8 6 10  < .001 9 7 11 < .001 6 4 8 < .001
TC/HDL ratio (reduction)
3 months over baseline 0.89  − 0.16 1.91 0.09 0.18 − 0.02 0.39 0.08 0.11 − 0.14 0.36 0.39
6 months over baseline 0.78  − 0.27 1.80 0.15 0.23 0.06 0.40 0.009 0.01 − 0.23 0.24 0.97
QRISK (reduction in %)
3 months over baseline 1.8 0.9 2.7  < .001 1.6 0.6 2.6 0.002 2.1 1.2 3.0 < .001
6 months over baseline 0.9  − 0.4 2.3 0.164 1.8 0.8 2.7 < .001 1.7 0.7 2.7 0.001