| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P for trend |
---|---|---|---|---|---|
No. of participants | 98,371 | 99,289 | 99,714 | 99,464 | Â |
No. of incident IBS | 1882 | 1797 | 1701 | 1749 | Â |
Follow-up, person-years | 1,192,803 | 1,197,965 | 1,199,435 | 1,185,959 | Â |
Follow-up, years | |||||
 Mean ± SD | 12.1 ± 1.8 | 12.1 ± 1.8 | 12.0 ± 1.9 | 11.9 ± 2.1 |  |
 Median (IQR) | 12.4 (11.7–13.1) | 12.4 (11.6–13.1) | 12.4 (11.6–13.1) | 12.3 (11.6–13.1) |  |
Hazard ratio for incident IBS (95%CI, P value) | |||||
 Adjusted model 1 | Reference | 1.15 (1.08–1.23) | 1.24 (1.16–1.33) | 1.36 (1.27–1.46) |  < 0.001 |
 Adjusted model 2 | Reference | 1.13 (1.06–1.21) | 1.20 (1.12–1.28) | 1.27 (1.19–1.37) |  < 0.001 |
 Adjusted model 3 | Reference | 1.12 (1.05–1.20) | 1.17 (1.10–1.26) | 1.21 (1.13–1.30) |  < 0.001 |