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Table 2 Frailty in individuals with and without mental disorders

From: Frailty in individuals with depression, bipolar disorder and anxiety disorders: longitudinal analyses of all-cause mortality

 

Model 1

Model 2

Frailty phenotype

OR

95% CI

OR

95% CI

 No mental disorder

Ref

–

–

Ref

–

–

 Depression

1.594

1.568

1.620

1.392

1.368

1.416

 Bipolar disorder

1.904

1.772

2.046

1.543

1.433

1.661

 Anxiety disorder

1.503

1.471

1.536

1.352

1.322

1.384

Frailty index

β

95% CI

β

95% CI

 No mental disorder

Ref

–

–

Ref

–

–

 Depression

0.045

0.044

0.045

0.026

0.026

0.027

 Bipolar disorder

0.060

0.058

0.063

0.036

0.034

0.038

 Anxiety disorder

0.047

0.046

0.048

0.029

0.028

0.029

  1. OR odds ratio, β ordinary least squares regression beta coefficient, CI confidence interval, Ref reference group. All Bonferroni-adjusted p-values < 0.001. Odds ratios indicate changes in odds of being frailer associated with being in the case group relative to the comparison group without mental disorders. Model 1—unadjusted; Model 2—adjusted for age, sex, ethnicity, highest qualification, Townsend deprivation index, cohabitation with spouse/partner, smoking status, alcohol intake frequency, systolic and diastolic blood pressure, body mass index, cholesterol, multimorbidity count and assessment centre