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Fig. 5 | BMC Medicine

Fig. 5

From: Dissection of transcriptome dysregulation and immune characterization in women with germline BRCA1 mutation at single-cell resolution

Fig. 5

Profiling T cells in BRCA1 carriers. A t-SNE plot displaying the CD3+CD8+ T cells in BRCA1 and non-BRCA1 carriers. B t-SNE plot showing the distribution of clonal TCRs and pie chart showing the percentage of clonal TCRs in BRCA1 and non-BRCA1 carriers. C Violin plot showing the PD1 expression level in clonal and non-clonal CD8+ T cells. D Violin plot showing the PD1 expression level in BRCA1 mutation carriers and normal controls for clonal CD8+ T cells. Statistical significance was estimated using a two-sided Wilcoxon rank-sum test

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